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KMID : 0364019940270070571
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Korean Journal of Thoracic and Cardiovascular Surgery
1994 Volume.27 No. 7 p.571 ~ p.575
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The Effect of Cardiopumonary Bypass on the Concentrations of Thyroid Hormone
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Abstract
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The hemodyanmic effects of thyroid hormone are well estabilished, and this hormone affects myocardial contractility, heart rate, and myocardial oxygen consumption. But the role of cardiopulmonary bypass on the thyroid function is not yet fully
understood. We have studied twelve patients(male and female patinets were equal in number) who were performed open heart surgery under cardiopulmonary bypass.
@ES The results are followed.
@EN 1) The serum level of T3 began to fall after cardiopulmonary bypass and sustained significanltly till 24 hours afer operation(p<0.05).
2) The concentrations of T4, Free T4, and TSH were slightly decreased after cardiopulmonary bypass but was maintained within normal range.
3) This above findings are similar to the "euthyroid sick syndrome" that is seen in severly ill patient.
4) We can propose that T3 would be effective in postoperative low cardiac output syndrome. (Korean J Thoracic Cardiovas Surg 1994; 27:571-5)
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